Safety and feasibility of Ommaya reservoir for intrathecal chemotherapy in patients with leptomeningeal disease
Our single-center cohort study suggests that the use of intrathecal chemotherapy via Ommaya reservoir in routine clinical practice is a safe and feasible option and should be considered for treatment and frequent disease monitoring in eligible patients with leptomeningeal disease. Neurologists, especially neuro-oncologists, can significantly contribute to the care of patients of leptomeningeal disease via administering intrathecal chemotherapy.
Authors
- Maciej M. Mrugała (ORCID: https://orcid.org/0000-0002-4027-7173)
- Shiv Shah (ORCID: https://orcid.org/0000-0001-6605-0877)
- Jenna H. Meyer
- C Murali Krishna
- Richard S. Zimmerman (ORCID: https://orcid.org/0000-0002-9911-6817)
- Shannon P. Fortin Ensign (ORCID: https://orcid.org/0000-0002-7433-528X)
- Eric Yancey
- Richard J Butterfield (ORCID: https://orcid.org/0000-0001-6758-2875)
- Ehab Harahsheh (ORCID: https://orcid.org/0000-0001-7706-422X)
- Mark Lyons (ORCID: https://orcid.org/0000-0001-8133-0295)
- Carl Ariete
- Bernard R. Bendok
Institutions
- Mayo Clinic in Arizona (US)
- Mayo Clinic Hospital (US)
- Neurological Surgery (US)
Publication Details
- Journal
- Neurologia i Neurochirurgia Polska
- Published
- 2025-11-05
- DOI
- https://doi.org/10.5603/pjnns.105907
- Primary Topic
- Brain Metastases and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00