Simulating a virtual tumor board with large language models: a pilot study in NSCLC patients receiving immunotherapy

An LLM primed with comprehensive guidelines can accurately and safely replicate MDT recommendations for complex NSCLC cases. The combination of guideline injection and meticulous prompt engineering is a critical strategy for ensuring LLM reliability. This positions these models as powerful decision-support tools to augment, not replace, expert clinical workflow.

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Publication Details

Journal
Immunotherapy
Published
2025-10-13
DOI
https://doi.org/10.1080/1750743x.2025.2580272
Primary Topic
Advances in Oncology and Radiotherapy
Type
article
Field-Weighted Citation Impact
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article

Simulating a virtual tumor board with large language models: a pilot study in NSCLC patients receiving immunotherapy

Rashad İsmayılov, Zafer Akçalı, Özden Altundağ
Immunotherapy
Advances in Oncology and Radiotherapy
article

Simulating a virtual tumor board with large language models: a pilot study in NSCLC patients receiving immunotherapy

Rashad İsmayılov, Zafer Akçalı, Özden Altundağ
article en

Abstract

An LLM primed with comprehensive guidelines can accurately and safely replicate MDT recommendations for complex NSCLC cases. The combination of guideline injection and meticulous prompt engineering is a critical strategy for ensuring LLM reliability. This positions these models as powerful decision-support tools to augment, not replace, expert clinical workflow.

ImmunotherapyVol. 17(15)
Başkent University (TR)
Openalex Percentile: Top 53%
Advances in Oncology and Radiotherapy
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Simulating a virtual tumor board with large language models: a pilot study in NSCLC patients receiving immunotherapy — Rashad İsmayılov, Zafer Akçalı, et al. · Immunotherapy (2025) | TGRS Research Map | TGRS