Renal capsule patient-derived xenograft model for gastric cancer: establishment and MRI characterization
Optimal conditions for establishing GC PDX models involve transplanting 2×2×2 mm tumor fragments within 2 hours. MRI enables sensitive tumor detection and accurate size quantification. T2WI was the most effective and efficient imaging technique. Providing an efficient preclinical model for personalized therapy of gastric cancer.
Authors
- Ewetse Paul Maswikiti (ORCID: https://orcid.org/0000-0001-7184-2270)
- Zhuanfang Wang
- Yuping Bai (ORCID: https://orcid.org/0000-0003-1896-277X)
- Lei Gao (ORCID: https://orcid.org/0000-0001-8848-553X)
- Jianming Shi (ORCID: https://orcid.org/0000-0003-0695-5660)
- Bin Ma (ORCID: https://orcid.org/0000-0002-0727-4536)
- Yuhan Wang (ORCID: https://orcid.org/0009-0000-6809-6780)
- Qian Liu (ORCID: https://orcid.org/0000-0002-1937-0568)
- Hao Chen (ORCID: https://orcid.org/0000-0001-9741-9403)
- Xiang Lin (ORCID: https://orcid.org/0000-0001-8183-1583)
- Zhenyu Yin (ORCID: https://orcid.org/0000-0002-1763-8460)
Institutions
- Lanzhou University Second Hospital (CN)
- Lanzhou University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-11-05
- DOI
- https://doi.org/10.3389/fimmu.2025.1683916
- Primary Topic
- Gastric Cancer Management and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00