Turner Syndrome and Hepatic Adenomas: A Case Report

This case report describes large hepatic adenomas in a 35-year-old woman with Turner syndrome (TS) who had long-standing oral estradiol exposure and metabolic syndrome. Patients with TS may be at increased risk of hepatic adenomas when compared to the general population. Future research papers should seek to understand the true incidence of hepatic adenomas in TS, whether we should implement routine imaging screening for hepatic adenomas without abnormal liver function labs, and whether transdermal estradiol is safe after a diagnosis of hepatic adenomas.

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Publication Details

Journal
Cureus
Published
2025-11-05
DOI
https://doi.org/10.7759/cureus.96137
Primary Topic
Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Type
article
Field-Weighted Citation Impact
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article

Turner Syndrome and Hepatic Adenomas: A Case Report

Sindy H. Wei, Susan Ahern
Cureus
Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
article

Turner Syndrome and Hepatic Adenomas: A Case Report

Sindy H. Wei, Susan Ahern
article en

Abstract

This case report describes large hepatic adenomas in a 35-year-old woman with Turner syndrome (TS) who had long-standing oral estradiol exposure and metabolic syndrome. Patients with TS may be at increased risk of hepatic adenomas when compared to the general population. Future research papers should seek to understand the true incidence of hepatic adenomas in TS, whether we should implement routine imaging screening for hepatic adenomas without abnormal liver function labs, and whether transdermal estradiol is safe after a diagnosis of hepatic adenomas.

CureusVol. 17(11)
University of California, Los Angeles (US), Diabetes Australia (AU)
Openalex Percentile: Top 65%
Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
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