Doxycycline Use in Adolescent Psychiatric Patients and Risk of Schizophrenia: An Emulated Target Trial

These findings raise the tentative but exciting possibility that doxycycline treatment may reduce schizophrenia risk in adolescent psychiatric patients.

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Institutions

Publication Details

Journal
American Journal of Psychiatry
Published
2025-11-05
DOI
https://doi.org/10.1176/appi.ajp.20240958
Citations
4
Primary Topic
Tryptophan and brain disorders
Type
article
Field-Weighted Citation Impact
2.31
Controls
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article

Doxycycline Use in Adolescent Psychiatric Patients and Risk of Schizophrenia: An Emulated Target Trial

Eero Kajantie, Colm Healy, Anna Pulakka, Hugh Ramsay et al.
4 citations
American Journal of Psychiatry
Tryptophan and brain disorders
2.31
article

Doxycycline Use in Adolescent Psychiatric Patients and Risk of Schizophrenia: An Emulated Target Trial

Eero Kajantie, Colm Healy, Anna Pulakka, Hugh Ramsay, Ian Kelleher, K. O’Connor, Fiona Boland, Johanna Metsälä, Ulla Lång, Katriina Heikkilä, Anne Lawlor, Juha Veijola
article en
4 citations

Abstract

These findings raise the tentative but exciting possibility that doxycycline treatment may reduce schizophrenia risk in adolescent psychiatric patients.

American Journal of PsychiatryVol. 183(2)
University College Dublin (IE), Norwegian University of Science and Technology (NO), University of Medicine and Health Sciences (KN), Health Service Executive (IE), Finnish Institute for Health and Welfare (FI), 22q11 Ireland (IE), St John of God Hospital (AU), Early Intervention Foundation (GB), University of Oulu (FI), University of Edinburgh (GB)
Openalex Percentile: Top 11%
Tryptophan and brain disorders
2.31
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Doxycycline Use in Adolescent Psychiatric Patients and Risk of Schizophrenia: An Emulated Target Trial — Eero Kajantie, Colm Healy, et al. · American Journal of Psychiatry (2025) | TGRS Research Map | TGRS