Aurora Kinase A inhibitor alisertib failed to exert its efficacy on TNBC cells due to consequential enrichment of polyploid giant cancer cells (PGCCs)

Authors

Apurba Laha (ORCID: https://orcid.org/0000-0001-7320-642X)
Sutapa Mukherjee (ORCID: https://orcid.org/0000-0002-4411-7257)
Parimal Karmakar (ORCID: https://orcid.org/0000-0002-9423-9906)
Salini Das (ORCID: https://orcid.org/0009-0008-2465-1656)
Elizabeth Mahapatra
Siddhartha Kar (ORCID: https://orcid.org/0000-0002-2314-1426)
Debomita Sengupta (ORCID: https://orcid.org/0000-0001-8359-1763)
Sagar Sen (ORCID: https://orcid.org/0000-0002-7803-9920)
Debanjan Thakur (ORCID: https://orcid.org/0009-0001-7128-8449)
Jayanta Chakrabarti
Srabanti Hajra

Institutions

Houston Methodist (US)
Jadavpur University (IN)
Chittaranjan National Cancer Institute (IN)

Publication Details

Journal: Discover Oncology
Published: 2025-11-05
DOI: https://doi.org/10.1007/s12672-025-03825-0
Citations: 1
Primary Topic: Microtubule and mitosis dynamics
Type: article
Field-Weighted Citation Impact: 1.15

Funders

University of Kalyani
Chittaranjan National Cancer Institute

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article

Aurora Kinase A inhibitor alisertib failed to exert its efficacy on TNBC cells due to consequential enrichment of polyploid giant cancer cells (PGCCs)

Apurba Laha, Sutapa Mukherjee, Parimal Karmakar, Salini Das et al.

Nov 5, 2025

1 citations

Discover Oncology

Microtubule and mitosis dynamics

1.15

article

Aurora Kinase A inhibitor alisertib failed to exert its efficacy on TNBC cells due to consequential enrichment of polyploid giant cancer cells (PGCCs)

Apurba Laha, Sutapa Mukherjee, Parimal Karmakar, Salini Das, Elizabeth Mahapatra, Siddhartha Kar, Debomita Sengupta, Sagar Sen, Debanjan Thakur, Jayanta Chakrabarti, Srabanti Hajra

November 5, 2025article en

1 citations

Abstract

No abstract available for this paper.

Discover OncologyVol. 16(1)

Houston Methodist (US), Jadavpur University (IN), Chittaranjan National Cancer Institute (IN)

University of Kalyani, Chittaranjan National Cancer Institute

Openalex Percentile: Top 18%

Microtubule and mitosis dynamics

1.15

DOI Open Access PDF OpenAlex

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