Cerebral infarction associated with adenomyosis: Two case reports with mechanistic insights and multidisciplinary management

This report highlights the multifactorial pathogenesis of adenomyosis complicated by CI, emphasizing the shared pathway of hypercoagulability, endothelial injury, thrombus formation, and embolic migration. A multidisciplinary, staged management approach is crucial, with acute-phase focus on reperfusion therapy and AUB control, followed by conservative treatments or hysterectomy for long-term management. Neuroprotection and the management of comorbidities are integral throughout. Hysterectomy remains the most effective strategy to prevent recurrence. The proposed framework provides evidence-based guidance for managing these complex cases, with implications for clinical practice and future research.