APPL1 concentration as a potential biomarker in early-onset preeclampsia: correlations with adiponectin-leptin dysregulation and adverse neonatal outcomes
Elevated APPL1 is a potential and novel biomarker for early-onset PE, and reflecting adiponectin-leptin dysregulation, glycolipid metabolic disturbances, and adverse neonatal prognosis. Its integration into clinical prediction models warrants further validation.
Authors
- Yan Huang (ORCID: https://orcid.org/0000-0002-1599-9086)
- Xiaoli Chi
- Qianmeng Zhu
- Yuzhen Zhou (ORCID: https://orcid.org/0000-0002-6978-3432)
Institutions
- Suzhou Traditional Chinese Medicine Hospital (CN)
Publication Details
- Journal
- BMC Pregnancy and Childbirth
- Published
- 2025-11-05
- DOI
- https://doi.org/10.1186/s12884-025-08368-4
- Primary Topic
- Pregnancy and preeclampsia studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Science and Technology Program of Suzhou