Probiotic-enhanced chemotherapy: Lactobacillus fermentum synergizes with vincristine to induce apoptosis via dual pathway activation in human cancer cells
L. fermentum enhanced vincristine-induced apoptosis and reduced the required drug dose, which may contribute to lowering vincristine-associated toxicity. These findings require confirmation through in vivo studies.
Authors
- Asghar Parsaei (ORCID: https://orcid.org/0000-0001-7852-8129)
- Abbas Asoudeh-Fard (ORCID: https://orcid.org/0000-0002-6552-5268)
- Mohadeseh Asoudeh-Fard
Institutions
- Tabriz University of Medical Sciences (IR)
- Université Sorbonne Paris Nord (FR)
- Islamic Azad University, Zahedan Branch (IR)
- Ragheb Esfahani Institute (IR)
- Université Paris 1 Panthéon-Sorbonne (FR)
Publication Details
- Journal
- Cancer Cell International
- Published
- 2025-11-05
- DOI
- https://doi.org/10.1186/s12935-025-04032-1
- Citations
- 3
- Primary Topic
- Probiotics and Fermented Foods
- Type
- article
- Field-Weighted Citation Impact
- 3.49
Funders
- Shiraz University of Medical Sciences
- Tabriz University of Medical Sciences
- Shiraz University
- University of Tabriz