Eosinophilic Cystitis: A Rare Disease with Common Presentations - A Case Series

Eosinophilic cystitis EC is a rare inflammatory condition of the urinary bladder characterized by a predominant infiltration of eosinophils into the bladder wall. About 200 cases of eosinophilic cystitis have been reported till date. The pathogenesis of EC remains uncertain but it is often linked to allergic reactions parasitic infections and certain medications. The three patients described in this series presented with lower urinary tract symptoms LUTS and hematuria. Diagnosis was ascertained by cystoscopy and tissue biopsy. In all three cases the lesion was completely excised and submitted for histopathological examination. All three patients received oral antihistamines for three weeks and one patient received oral prednisolone. None of the patients showed recurrence during follow-up. A combination of imaging studies urinalysis and histopathological biopsy can effectively confirm the condition. In our case series early diagnosis and appropriate treatment led to favorable outcomes.