Is the association of cannabis use and stroke frequency-dependent: A cross-sectional analysis of the NIH all of us research program
In this large, nationally representative study, cannabis use was associated with stroke through two distinct, subtype-specific patterns. Odds of ischemic stroke demonstrated a clear dose-response relationship concentrated among frequent (weekly or daily) users, while odds of hemorrhagic stroke were elevated across all frequencies of use. These findings highlight the need to incorporate detailed cannabis use assessment into routine cerebrovascular risk stratification.
Authors
- Evan Luther (ORCID: https://orcid.org/0000-0001-9164-4984)
- Jeffrey M. Katz (ORCID: https://orcid.org/0000-0002-8193-3683)
- Barnabas Obeng-Gyasi (ORCID: https://orcid.org/0000-0003-3346-1631)
- Aladine A. Elsamadicy (ORCID: https://orcid.org/0000-0002-7658-6461)
- Seul‐Ki Jeong (ORCID: https://orcid.org/0000-0002-9868-621X)
- Ethan Brown (ORCID: https://orcid.org/0009-0003-6933-0745)
- Timothy G. White (ORCID: https://orcid.org/0000-0002-3604-4334)
- Richard Libman (ORCID: https://orcid.org/0000-0002-3978-7985)
- Daniel Schneider (ORCID: https://orcid.org/0009-0008-3330-455X)
Institutions
- Northwell Health (US)
- Allegheny Health Network (US)
- The Ohio State University Wexner Medical Center (US)
- Donald & Barbara Zucker School of Medicine at Hofstra/Northwell (US)
- Neurological Surgery (US)
Publication Details
- Journal
- International Journal of Stroke
- Published
- 2025-11-05
- DOI
- https://doi.org/10.1177/17474930251396481
- Primary Topic
- Cannabis and Cannabinoid Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00