Impact of Psychiatric Comorbidities on Quality of Life in Patients with Dermatological Conditions: A Cross-Sectional Study

Background Dermatological conditions significantly affect patients quality of life and are frequently associated with psychiatric comorbidities such as depression and anxiety. Understanding the sociodemographic dermatological and psychiatric profiles of the affected individuals is essential for providing holistic care.Aim To evaluate the sociodemographic characteristics dermatological profiles and psychiatric comorbidities of patients attending a dermatology outpatient department and examine the association between quality of life and psychiatric parameters.Methods This cross-sectional study included 114 patients with dermatological disease. Data were collected using validated tools including the Dermatology Life Quality Index DLQI Patient Health Questionnaire-9 PHQ-9 Hamilton Depression Rating Scale HAM-D Generalized Anxiety Disorder-7 GAD-7 and Patient Health Questionnaire-15 PHQ-15. Descriptive statistics were used to summarize the data and associations were analyzed using Chi-squared tests logistic regression and correlation analysis. Receiver operating characteristic ROC curve analysis was used to evaluate the predictive utility of PHQ-9 for high DLQI scores.Results The majority of the patients were young unmarried and urban residents with acne 36.0 and fungal infections 27.2 being the most common dermatological conditions. Psychiatric comorbidities were prevalent with 60.5 of participants experiencing depression and 44.7 reporting anxiety. Higher DLQI scores were significantly associated with the PHQ-9 P lt 0.05 HAM-D P lt0.05 and GAD-7 P lt0.05 scores. Logistic regression identified the PHQ-9 and HAM-D as independent predictors of high DLQI scores P lt0.05. ROC analysis of the PHQ-9 yielded an AUC of 0.72 suggesting moderate accuracy in predicting an impaired quality of life.Conclusion Dermatological conditions are associated with significant psychiatric comorbidities and quality-of-life impairments. Depression and anxiety are key predictors of poor quality of life. These findings emphasize the need for integrated dermatology and mental health care to address the holistic needs of patients.