Protective effects of Apelin-13 on steroid-induced osteonecrosis of the femoral head in rats
Apelin-13 demonstrates protective effects against SONFH by reducing oxidative stress, apoptosis, and improving vascularization. It may represent a promising noninvasive therapeutic strategy for early-stage ONFH.
Authors
- E. Balci (ORCID: https://orcid.org/0000-0002-1565-9620)
- Mustafa Fatih Daşcı (ORCID: https://orcid.org/0000-0002-2443-4802)
- Yiğit Güleryüz (ORCID: https://orcid.org/0000-0002-9220-9578)
- Büşra Yaprak Bayrak (ORCID: https://orcid.org/0000-0002-0537-3127)
- Muhammed Uslu (ORCID: https://orcid.org/0000-0002-1810-2713)
- Ozan Beytemür (ORCID: https://orcid.org/0000-0002-9608-7280)
- Ozancan Biçer (ORCID: https://orcid.org/0000-0002-6080-177X)
- Yiğit Önaloğlu (ORCID: https://orcid.org/0000-0002-3893-797X)
Institutions
- University of Health Science (KH)
- State Hospital (GB)
- Sivas State Hospital (TR)
- İstanbul Başakşehir Çam ve Sakura Şehir Hastanesi
- Kocaeli Üniversitesi (TR)
Publication Details
- Journal
- Connective Tissue Research
- Published
- 2025-11-05
- DOI
- https://doi.org/10.1080/03008207.2025.2573679
- Primary Topic
- Apelin-related biomedical research
- Type
- article
- Field-Weighted Citation Impact
- 0.00