Gestational age-dependent clinical characteristics of necrotizing enterocolitis-associated intestinal perforation: a 10-year cohort study
GA-specific NEC-IP mechanisms mandate: (1) preterm-focused ileal exploration & Gram-negative coverage, (2) term-focused retroperitoneal debridement & Gram-positive control, and (3) GA-stratified diagnostic framework integrating clinical signs and imaging. This precision approach reduces missed perforations and surgical delays.
Authors
- Weihong Yue
- Gege Liu
- Hong Wei (ORCID: https://orcid.org/0000-0002-5953-0714)
- Feng Chen (ORCID: https://orcid.org/0000-0002-9054-943X)
- Xia Liu (ORCID: https://orcid.org/0000-0002-0039-4754)
- Ya Hu (ORCID: https://orcid.org/0000-0002-2216-0908)
Institutions
- China International Science and Technology Cooperation (CN)
- Chongqing Maternal and Child Health Hospital (CN)
- Chongqing Population and Family Planning Science and Technology Research Institute (CN)
- Children's Hospital of Chongqing Medical University (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- BMC Gastroenterology
- Published
- 2025-11-05
- DOI
- https://doi.org/10.1186/s12876-025-04381-1
- Primary Topic
- Infant Nutrition and Health
- Type
- article
- Field-Weighted Citation Impact
- 0.00