HSP47 inhibitor Col003 may attenuates neurological impairment in chronic ischemic stroke rats by inhibiting LCN2
In rats with chronic ischemic stroke, Col03 may lessen the size of the cerebral infarction and neurological impairments by blocking LCN2 through the JAK2/STAT3 signaling pathway.
Authors
- Tingting Liang (ORCID: https://orcid.org/0000-0003-1607-5771)
- Jingli Liu (ORCID: https://orcid.org/0000-0002-5375-7491)
- Kejian Zhou
- Jinpin Li
- Haoying Li (ORCID: https://orcid.org/0000-0001-6752-5328)
- Mengyu Deng (ORCID: https://orcid.org/0000-0001-9203-4846)
- Xiaoyun Xie (ORCID: https://orcid.org/0000-0003-0921-7081)
- Yuliang Xie (ORCID: https://orcid.org/0000-0001-6084-7113)
Institutions
- Guangxi Medical University (CN)
- First Affiliated Hospital of GuangXi Medical University (CN)
Publication Details
- Journal
- Neurological Research
- Published
- 2025-11-04
- DOI
- https://doi.org/10.1080/01616412.2025.2579718
- Primary Topic
- Heat shock proteins research
- Type
- article
- Field-Weighted Citation Impact
- 0.00