Mendelian Randomization Analysis Reveals No Causal Genetic Link Between Dentofacial Anomalies and Dental Caries.
Our findings suggest that dentofacial anomalies, including malocclusion, do not have a direct genetic impact on dental health. These results emphasize the importance of prioritizing oral hygiene practices, dietary interventions, and targeted preventive strategies over corrective orthodontic approaches in clinical management to improve dental health outcomes.
Authors
- Jinhan Yu
- Ben Ma (ORCID: https://orcid.org/0000-0002-8741-4104)
- Qi Fan (ORCID: https://orcid.org/0000-0003-3168-0347)
- Xiaomeng Wang (ORCID: https://orcid.org/0000-0002-4516-4389)
- Gongjie Yuan (ORCID: https://orcid.org/0009-0005-8304-5435)
Publication Details
- Journal
- PubMed
- Published
- 2025-11-04
- DOI
- https://doi.org/10.3290/j.ohpd.c_2319
- Primary Topic
- dental development and anomalies
- Type
- article
- Field-Weighted Citation Impact
- 0.00