Focal Spikes Versus Sharp Waves: Do They Differ?

In our series, discharge duration did not correlate with seizure frequency or number of antiseizures medicines. Only 13% of patients had exclusive spikes or sharp waves, suggesting that duration of an individual discharge is not a defining characteristic of that person's epilepsy. Although this study is small and preliminary, it suggests that the distinction between spike and sharp waves at 70 ms may not be clinically relevant and perhaps all epileptiform discharges could be called spikes.

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Publication Details

Journal
Journal of Clinical Neurophysiology
Published
2025-11-03
DOI
https://doi.org/10.1097/wnp.0000000000001223
Primary Topic
Epilepsy research and treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Focal Spikes Versus Sharp Waves: Do They Differ?

F. Zhang, Alexandria M. Jensen, Spencer Nam, Robert S. Fisher et al.
Journal of Clinical Neurophysiology
Epilepsy research and treatment
article

Focal Spikes Versus Sharp Waves: Do They Differ?

F. Zhang, Alexandria M. Jensen, Spencer Nam, Robert S. Fisher, Manveer Dilts-Garcha, Olivia Marais
article en

Abstract

In our series, discharge duration did not correlate with seizure frequency or number of antiseizures medicines. Only 13% of patients had exclusive spikes or sharp waves, suggesting that duration of an individual discharge is not a defining characteristic of that person's epilepsy. Although this study is small and preliminary, it suggests that the distinction between spike and sharp waves at 70 ms may not be clinically relevant and perhaps all epileptiform discharges could be called spikes.

Journal of Clinical Neurophysiology
Wilford Hall Ambulatory Surgical Center (US), Thion Medical (France) (FR), Stanford University (US)
Openalex Percentile: Top 61%
Epilepsy research and treatment
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