Downregulation of KHSRP enhances carboplatin sensitivity in non-small cell lung cancer
These findings demonstrate that silencing of KHSRP enhances the drug sensitivity of carboplatin in NSCLC, potentially mediated through the inhibition of HMGB1. Targeting KHSRP may represent a promising therapeutic strategy to improve chemotherapy efficacy in NSCLC.
Authors
- Pengjie Yang (ORCID: https://orcid.org/0000-0003-4199-8295)
- Bateer Han
- Chuanhui Teng
- Yanqing Gao (ORCID: https://orcid.org/0000-0002-0989-0631)
- Lan Bao (ORCID: https://orcid.org/0000-0001-9269-9565)
- Haoyuan Li (ORCID: https://orcid.org/0000-0002-7030-8065)
- Wen Bao
- Shuguang Bao
Institutions
- Inner Mongolia Medical University (CN)
Publication Details
- Journal
- Hereditas
- Published
- 2025-11-05
- DOI
- https://doi.org/10.1186/s41065-025-00584-4
- Primary Topic
- Advanced Glycation End Products research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Inner Mongolia Medical University