Dual impact of interleukin-17 A blockade on inflammatory and stromal pathways in peripheral spondyloarthritis
Our findings provide new insights into the molecular mechanisms of IL-17 A blockade in pSpA, underscoring its unique role in selectively targeting bone-remodeling processes specific to the joints of individuals with SpA.
Authors
- Nataliya Yeremenko
- Ihsan Hammoura (ORCID: https://orcid.org/0000-0002-8232-7415)
- Sander W. Tas (ORCID: https://orcid.org/0000-0002-8940-1788)
- Renée H. Fiechter (ORCID: https://orcid.org/0000-0002-2317-2687)
- Henriëtte M. Y. de Jong (ORCID: https://orcid.org/0000-0003-1818-180X)
- Dominique Baeten (ORCID: https://orcid.org/0000-0002-0121-5543)
- Inka A. Fluri
- Leonieke van Mens (ORCID: https://orcid.org/0000-0003-0992-4448)
- Marleen G H van de Sande (ORCID: https://orcid.org/0000-0003-0966-878X)
Institutions
- Amsterdam University Medical Centers (NL)
Publication Details
- Journal
- Arthritis Research & Therapy
- Published
- 2025-11-05
- DOI
- https://doi.org/10.1186/s13075-025-03638-0
- Primary Topic
- Spondyloarthritis Studies and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00