TelOMpy enables single-molecule resolution of telomere length from optical genome mapping data
TelOMpy enables direct measurement of absolute telomere lengths at the single-molecule level across thousands of telomeres per sample. This approach eliminates errors associated with indirect methods and offers high analytical power and reproducibility, representing a significant advancement in telomere length analysis.
Authors
- Željka Pezer (ORCID: https://orcid.org/0000-0001-6543-5513)
- Sunčica Stipoljev (ORCID: https://orcid.org/0000-0003-4635-6777)
- Ivan Pokrovac
Institutions
- Ruđer Bošković Institute (HR)
Publication Details
- Journal
- BMC Biology
- Published
- 2025-11-05
- DOI
- https://doi.org/10.1186/s12915-025-02437-y
- Citations
- 1
- Primary Topic
- Telomeres, Telomerase, and Senescence
- Type
- article
- Field-Weighted Citation Impact
- 1.16
Funders
- Sveučilište u Zagrebu
- Hrvatska Zaklada za Znanost