Efficacy and Safety of Ulinastatin in Post-traumatic Sepsis: A Randomized Controlled Trial
While the 28-day mortality rate did not differ significantly between the two groups, ulinastatin was associated with shorter ICU and hospital stays, improvements in inflammatory markers and organ function, and demonstrated a favorable safety profile.
Authors
- Meng-Fei Han
- Weijun Chen (ORCID: https://orcid.org/0000-0002-1260-3488)
- Rui Liu (ORCID: https://orcid.org/0000-0002-5039-7419)
- Kongbo Lv
- Zhizhou Yang
- Ao Yang (ORCID: https://orcid.org/0000-0003-1516-7746)
Institutions
- Nanjing University of Chinese Medicine (CN)
- Second Affiliated Hospital of Nanjing Medical University (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Drugs in R&D
- Published
- 2025-11-05
- DOI
- https://doi.org/10.1007/s40268-025-00524-7
- Primary Topic
- Immune Response and Inflammation
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Nanjing University
- Bijzonder Onderzoeksfonds UGent