Induction of helical chirality in tetrahedral transition metal complexes with non-bridging monodentate oxazolines
Chirality on C4-atoms of non-bridging monodentate oxazolines direct stereoselective formation of helical chirality in [M(1)<sub>2</sub>X<sub>2</sub>] tetrahedral metal complexes of zinc(II), cadmium(II) and cobalt(II) halides, as revealed by their crystal structures. This feature was used to prepare a set of helically chiral derivatives with various structural motifs. In particular, bulkiness, non-covalent interactions and choice of point chirality combinations were found to strongly affect induction of chirality on the metal atom. The substituent influence on complexation and chiral induction was analyzed using XRD-diffraction studies, NMR, UV-Vis and CD spectroscopies, as well as DFT calculations.
Authors
- Zoran Kokan (ORCID: https://orcid.org/0000-0001-6815-6026)
- Srećko I. Kirin (ORCID: https://orcid.org/0000-0002-0500-2422)
- Robert Vianello (ORCID: https://orcid.org/0000-0003-1779-4524)
- Berislav Perić (ORCID: https://orcid.org/0000-0002-2397-2836)
- Ernest Sanders
- Tamara Rinkovec (ORCID: https://orcid.org/0000-0002-2561-3052)
- Zoran Štefanić
- Marija Bakija (ORCID: https://orcid.org/0000-0002-4302-6257)
Institutions
- Ruđer Bošković Institute (HR)
Publication Details
- Journal
- Dalton Transactions
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5dt02399h
- Primary Topic
- Axial and Atropisomeric Chirality Synthesis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- European Commission
- Hrvatska Zaklada za Znanost
- European Regional Development Fund