A standardized extract of Centella asiatica (ECa 233) alleviates brain injury and improves brain function in β-thalassemia mice with iron overload
These results suggest that the beneficial effect of ECa 233 may be partially due to decreased iron accumulation in the brain. ECa 233 may be used as an adjuvant with an iron chelator to prevent iron-induced neurodegenerative complications in individuals with β-thalassemia.
Authors
- Mayuree H. Tantisira (ORCID: https://orcid.org/0000-0002-5321-8076)
- Sukonthar Ngampramuan (ORCID: https://orcid.org/0000-0001-8903-6955)
- Somkiat Huaijantug (ORCID: https://orcid.org/0000-0002-1833-1567)
- Saovaros Svasti (ORCID: https://orcid.org/0000-0001-8334-9838)
- Paranee Yatmark (ORCID: https://orcid.org/0000-0002-0017-4081)
- Noppawan Phumala Morales (ORCID: https://orcid.org/0000-0002-5365-2884)
- Puntita Anutagerngkun
Institutions
- Burapha University (TH)
- Chulalongkorn University (TH)
- Mahidol University (TH)
Publication Details
- Journal
- BMC Complementary Medicine and Therapies
- Published
- 2025-11-05
- DOI
- https://doi.org/10.1186/s12906-025-05145-w
- Primary Topic
- Medicinal Plants and Neuroprotection
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Mahidol University
- Agricultural Research Development Agency