Appraisal the significance of completion hysterectomy after definitive concurrent chemoradiotherapy for patients with locally advanced cervical adenocarcinoma: the ATTRACT study

Completion hysterectomy after CCRT could increase DMFS for LACA patients, while not every LACA patient would retain OS benefit from surgery, except for those with positive UI. Survival differences existed in different degrees of RD among patients receiving post-radiation surgery and postoperative chemotherapy, demonstrating a trend toward PFS benefit for patients with RD≥1/2MI.

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Publication Details

Journal
International Journal of Surgery
Published
2025-11-05
DOI
https://doi.org/10.1097/js9.0000000000003549
Primary Topic
Endometrial and Cervical Cancer Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Appraisal the significance of completion hysterectomy after definitive concurrent chemoradiotherapy for patients with locally advanced cervical adenocarcinoma: the ATTRACT study

Jiawei Zhu, Yonglan He, Xilin Yang, Qiu Guan et al.
International Journal of Surgery
Endometrial and Cervical Cancer Treatments
article

Appraisal the significance of completion hysterectomy after definitive concurrent chemoradiotherapy for patients with locally advanced cervical adenocarcinoma: the ATTRACT study

Jiawei Zhu, Yonglan He, Xilin Yang, Qiu Guan, Zhiwei Yang, Yue Zhang, Junfang Yan, Hui Guan, Yan You, Yuncan Zhou, Peng Peng, Zheng Miao, Ke Hu, Fu-Quan Zhang
article en

Abstract

Completion hysterectomy after CCRT could increase DMFS for LACA patients, while not every LACA patient would retain OS benefit from surgery, except for those with positive UI. Survival differences existed in different degrees of RD among patients receiving post-radiation surgery and postoperative chemotherapy, demonstrating a trend toward PFS benefit for patients with RD≥1/2MI.

International Journal of SurgeryVol. 112(1)
Chinese Academy of Medical Sciences & Peking Union Medical College (CN), Peking Union Medical College Hospital (CN)
Openalex Percentile: Top 59%
Endometrial and Cervical Cancer Treatments
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