Rapunzel syndrome: Trichobezoar‐induced pancreatitis unraveled

Trichobezoars are rare hair-based intraluminal foreign bodies that may cause significant gastrointestinal complications, particularly when extending into the duodenum as in Rapunzel syndrome. We report the case of an 11-year-old girl with sensory processing difficulties and undiagnosed avoidant/restrictive food intake disorder (ARFID), who presented with 1 month of worsening abdominal pain, emesis, and elevated lipase (>1200 U/L). Imaging revealed a large gastric bezoar with duodenal extension and acute necrotizing pancreatitis. Surgical removal with anterior gastrotomy confirmed presence of a trichobezoar composed of hair and food material. Postoperative management included broad-spectrum antibiotics, pain control, and psychological support. The patient recovered well and was discharged with follow-up for autism spectrum disorder and ARFID. This case highlights a rare but serious complication of trichobezoars and underscores the importance of multidisciplinary care in patients with behavioral feeding disorders and gastrointestinal complications.

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Publication Details

Journal
JPGN Reports
Published
2025-11-05
DOI
https://doi.org/10.1002/jpr3.70108
Primary Topic
Intestinal and Peritoneal Adhesions
Type
article
Field-Weighted Citation Impact
0.00
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article

Rapunzel syndrome: Trichobezoar‐induced pancreatitis unraveled

Slade Matthews, Halen Scott, Megha S. Mehta, Ashley Polachek et al.
JPGN Reports
Intestinal and Peritoneal Adhesions
article

Rapunzel syndrome: Trichobezoar‐induced pancreatitis unraveled

Slade Matthews, Halen Scott, Megha S. Mehta, Ashley Polachek, Alisha Sansguiri
article en

Abstract

Trichobezoars are rare hair-based intraluminal foreign bodies that may cause significant gastrointestinal complications, particularly when extending into the duodenum as in Rapunzel syndrome. We report the case of an 11-year-old girl with sensory processing difficulties and undiagnosed avoidant/restrictive food intake disorder (ARFID), who presented with 1 month of worsening abdominal pain, emesis, and elevated lipase (>1200 U/L). Imaging revealed a large gastric bezoar with duodenal extension and acute necrotizing pancreatitis. Surgical removal with anterior gastrotomy confirmed presence of a trichobezoar composed of hair and food material. Postoperative management included broad-spectrum antibiotics, pain control, and psychological support. The patient recovered well and was discharged with follow-up for autism spectrum disorder and ARFID. This case highlights a rare but serious complication of trichobezoars and underscores the importance of multidisciplinary care in patients with behavioral feeding disorders and gastrointestinal complications.

JPGN ReportsVol. 7(1)
Children's Medical Center (US), The University of Texas Southwestern Medical Center (US)
Openalex Percentile: Top 49%
Intestinal and Peritoneal Adhesions
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Rapunzel syndrome: Trichobezoar‐induced pancreatitis unraveled — Slade Matthews, Halen Scott, et al. · JPGN Reports (2025) | TGRS Research Map | TGRS