Rapid evaluation of muscularis propria in transurethral resection of bladder tumour specimens using non-linear microscopy (NLM)
This proof-of-concept study supports the feasibility of NLM for intraoperative MP assessment during TURBT. By providing rapid, high-resolution and non-destructive tissue evaluation, NLM has the potential to improve staging accuracy, optimise intraoperative surgical decision-making and reduce the need for repeat TURBT.
Authors
- James G. Fujimoto (ORCID: https://orcid.org/0000-0002-0828-4357)
- Timothy D. Weber (ORCID: https://orcid.org/0000-0002-9948-0256)
- Boris Gershman (ORCID: https://orcid.org/0000-0001-5191-7255)
- Seymour Rosen (ORCID: https://orcid.org/0000-0002-0832-5139)
- Lisha Wang (ORCID: https://orcid.org/0000-0002-4033-9856)
- Yue Sun (ORCID: https://orcid.org/0009-0007-4499-5221)
Institutions
- Beth Israel Deaconess Medical Center (US)
- Massachusetts Institute of Technology (US)
Publication Details
- Journal
- Journal of Clinical Pathology
- Published
- 2025-11-04
- DOI
- https://doi.org/10.1136/jcp-2025-210368
- Primary Topic
- Bladder and Urothelial Cancer Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00