π-Delocalization and aromaticity as key factors in regioselective ring closure of fused triazolopyrimidines: an experimental–theoretical approach
This study presents a comprehensive synthetic and computational investigation of the regioselective ring-closing reactions in the synthesis of three pyrazolo[4,3- e ][1,2,4]triazolo[4,3- a ]pyrimidine (PTP) derivatives, namely 3-H, 3-Me, and 3-Et.
Authors
- Hossein Eshghi (ORCID: https://orcid.org/0000-0002-8417-220X)
- Mohadeseh Seddighi
- Hossein Sabet‐Sarvestani (ORCID: https://orcid.org/0000-0002-5461-2868)
- Nazanin Norozi Shad
Institutions
- Academic Center for Education, Culture and Research (IR)
- Ferdowsi University of Mashhad (IR)
Publication Details
- Journal
- New Journal of Chemistry
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5nj03365a
- Primary Topic
- Synthesis and Reactivity of Heterocycles
- Type
- article
- Field-Weighted Citation Impact
- 0.00