Drug‐Induced Liver Failure Following Topical Minoxidil: A Case Report

This is the first evidence of severe drug-induced liver failure associated with topical minoxidil. It underscores the potential for hepatotoxicity even with over-the-counter drugs that are thought to have minimal systemic absorption. The rapid improvement after discontinuation of the drug and exclusion of differential diagnoses suggests a causal relationship. In cases of severe liver failure of unclear origin, all substances should be considered in the case history.

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Publication Details

Journal
Case Reports in Gastrointestinal Medicine
Published
2025-01-01
DOI
https://doi.org/10.1155/crgm/1040092
Citations
1
Primary Topic
Drug-Induced Hepatotoxicity and Protection
Type
article
Field-Weighted Citation Impact
1.56
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article

Drug‐Induced Liver Failure Following Topical Minoxidil: A Case Report

Carlos Fritzsche, Andreas Erbersdobler, Katrin Premke, Micha Loebermann et al.
1 citations
Case Reports in Gastrointestinal Medicine
Drug-Induced Hepatotoxicity and Protection
1.56
article

Drug‐Induced Liver Failure Following Topical Minoxidil: A Case Report

Carlos Fritzsche, Andreas Erbersdobler, Katrin Premke, Micha Loebermann, Matthias Kästner
article en
1 citations

Abstract

This is the first evidence of severe drug-induced liver failure associated with topical minoxidil. It underscores the potential for hepatotoxicity even with over-the-counter drugs that are thought to have minimal systemic absorption. The rapid improvement after discontinuation of the drug and exclusion of differential diagnoses suggests a causal relationship. In cases of severe liver failure of unclear origin, all substances should be considered in the case history.

Case Reports in Gastrointestinal MedicineVol. 2025(1)
University of Rostock (DE)
Openalex Percentile: Top 14%
Drug-Induced Hepatotoxicity and Protection
1.56
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