Short-term outcomes associated with fluoxetine, low-frequency rTMS, and their combination in first-onset adolescent OCD: a single-center retrospective cohort

The findings suggest that combining fluoxetine with LF-rTMS may be associated with greater short-term improvements in symptom severity, cognitive function, and neural activity compared with monotherapy, while maintaining a favorable safety profile.

Authors

Chunfeng Hu (ORCID: https://orcid.org/0000-0003-0882-9916)
Huan Wang (ORCID: https://orcid.org/0000-0002-3816-9552)
Haixia Wang (ORCID: https://orcid.org/0000-0002-8165-7009)
Meng Jiang (ORCID: https://orcid.org/0000-0003-1984-1267)
Zhenzhen Yang
Tao Yang (ORCID: https://orcid.org/0000-0002-7795-6081)

Institutions

Jining Traditional Chinese Medicine Hospital (CN)

Publication Details

Journal: Frontiers in Psychiatry
Published: 2025-11-05
DOI: https://doi.org/10.3389/fpsyt.2025.1663611
Primary Topic: Obsessive-Compulsive Spectrum Disorders
Type: article
Field-Weighted Citation Impact: 0.00

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article

Short-term outcomes associated with fluoxetine, low-frequency rTMS, and their combination in first-onset adolescent OCD: a single-center retrospective cohort

Chunfeng Hu, Huan Wang, Haixia Wang, Meng Jiang et al.

Nov 5, 2025

Frontiers in Psychiatry

Obsessive-Compulsive Spectrum Disorders

article

Short-term outcomes associated with fluoxetine, low-frequency rTMS, and their combination in first-onset adolescent OCD: a single-center retrospective cohort

Chunfeng Hu, Huan Wang, Haixia Wang, Meng Jiang, Zhenzhen Yang, Tao Yang

November 5, 2025article en

Abstract

The findings suggest that combining fluoxetine with LF-rTMS may be associated with greater short-term improvements in symptom severity, cognitive function, and neural activity compared with monotherapy, while maintaining a favorable safety profile.

Frontiers in PsychiatryVol. 16

Jining Traditional Chinese Medicine Hospital (CN)

Openalex Percentile: Top 56%

Obsessive-Compulsive Spectrum Disorders

DOI Open Access PDF OpenAlex

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Short-term outcomes associated with fluoxetine, low-frequency rTMS, and their combination in first-onset adolescent OCD: a single-center retrospective cohort — Chunfeng Hu, Huan Wang, et al. · Frontiers in Psychiatry (2025) | TGRS Research Map | TGRS