Soluble HLA-G is related to malignant melanocytic lesions and previous oncological disease may increase circulating HLA-G bearing large extracellular vesicles
These results may suggest that sHLA-G may be a promising biomarker to predict malignant melanocytic lesions; however, it is important to consider previous neoplasms. Also, its application may be relevant for specific histological subtypes and lesion sites.
Authors
- Thalia Medeiros (ORCID: https://orcid.org/0000-0002-5642-4027)
- Andréa Alice Silva (ORCID: https://orcid.org/0000-0001-5856-6128)
- Fabiana Rabe Carvalho (ORCID: https://orcid.org/0000-0002-4713-233X)
- Maria Sallydelândia de Farias Araújo (ORCID: https://orcid.org/0000-0002-3255-2024)
- Fernanda G. De Felice (ORCID: https://orcid.org/0000-0001-8358-0589)
- Carlos Arthur de Figueiredo Athayde (ORCID: https://orcid.org/0009-0003-0169-2264)
- Flávio Barbosa Luz (ORCID: https://orcid.org/0000-0001-7021-9970)
- Luciana Pantaleão (ORCID: https://orcid.org/0000-0001-7480-2530)
- Paulo Rogério Beltramin da Fonseca (ORCID: https://orcid.org/0009-0003-4123-7493)
- Élcio Gerônimo de Oliveira
- Kianny Kimberly Silva-Krebs
- Istéfani Luciene Dayse-Silva
Institutions
- Universidade Federal Fluminense (BR)
- D’Or Institute for Research and Education (BR)
- Hospital Universitário Antônio Pedro (BR)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-11-05
- DOI
- https://doi.org/10.3389/fimmu.2025.1670611
- Citations
- 1
- Primary Topic
- Reproductive System and Pregnancy
- Type
- article
- Field-Weighted Citation Impact
- 0.80
Funders
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
- Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro
- Universidade Federal do Rio de Janeiro