MOLECULAR SURVEILLANCE IN BONE MARROW FAILURE: PREDICTIVE VALUE OF CLONAL HEMATOPOIESIS
Background and Aims: Bone marrow failure (BMF) syndromes exhibit clonal hematopoiesis (CH) with variable MDS risk. We evaluated the diagnostic predictive value of somatic alterations and compared peripheral blood (PB) versus bone marrow (BM) sampling for CH detection.
Authors
- Alyssa L. Kennedy (ORCID: https://orcid.org/0000-0001-7948-5933)
- Marcin W. Włodarski (ORCID: https://orcid.org/0000-0001-6638-9643)
- Michelle Boals
- Nathan Gray (ORCID: https://orcid.org/0009-0000-8030-9670)
- Sara E. Lewis (ORCID: https://orcid.org/0000-0001-8119-7076)
- Kunal Ray (ORCID: https://orcid.org/0000-0001-9989-1760)
- Enrico Attardi (ORCID: https://orcid.org/0009-0008-4801-5048)
- Passant Shaker (ORCID: https://orcid.org/0000-0001-9750-9310)
- Melvanique Hale
- Jessica Uhrich
Institutions
- St. Jude Children's Research Hospital (US)
Publication Details
- Journal
- EJC Paediatric Oncology
- Published
- 2025-11-05
- DOI
- https://doi.org/10.1016/j.ejcped.2025.100329
- Primary Topic
- Abdominal Trauma and Injuries
- Type
- article
- Field-Weighted Citation Impact
- 0.00