Placental Angiogenic Imbalance and Its Association With Adverse Outcomes in Congenital Heart Disease Pregnancies
Pregnant women with CHD exhibited a placental angiogenic imbalance, with higher sFlt-1 and lower PlGF in late pregnancy than controls. This imbalance was associated with a higher risk of adverse pregnancy outcomes, particularly in women with high sFlt-1.
Authors
- Julie Hotton
- Frédéric Debiève (ORCID: https://orcid.org/0000-0002-8033-2245)
- Agnès Pasquet (ORCID: https://orcid.org/0000-0002-3778-6604)
- David Vancraeynest (ORCID: https://orcid.org/0000-0002-5231-2984)
- Nour Rahnama
- Didier Gruson (ORCID: https://orcid.org/0000-0002-1199-5125)
- Christophe Beauloye (ORCID: https://orcid.org/0000-0002-1665-8267)
- Nassiba Menghoum (ORCID: https://orcid.org/0009-0000-2575-7091)
- Arthur Colson (ORCID: https://orcid.org/0000-0002-8691-123X)
- Sophie Piérard (ORCID: https://orcid.org/0000-0003-0078-9788)
Institutions
- Cliniques Universitaires Saint-Luc (BE)
- UCLouvain (BE)
Publication Details
- Journal
- JACC Advances
- Published
- 2025-11-05
- DOI
- https://doi.org/10.1016/j.jacadv.2025.102301
- Primary Topic
- Pregnancy and preeclampsia studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00