THE GENOMIC LANDSCAPE OF JUVENILE MYELOMONOCYTIC LEUKEMIA ON WHOLE EXOME SEQUENCING

Background: Juvenile Myelomonocytic Leukemia (JMML) is a rare myelodysplastic/myeloproliferative neoplasm. The RAS-pathway related genes are most commonly mutated in JMML. Other secondary mutations/alternative pathways are also thought to be involved in the pathogenesis. This study was prospectively done to map the mutational landscape of newly diagnosed and treatment naive JMML patients.

Authors

Meena Jagdish Prasad
Harsh Goel (ORCID: https://orcid.org/0000-0003-3904-7343)
Anita Chopra (ORCID: https://orcid.org/0000-0002-0238-8702)
Ravi Kumar Majhi
Pranay Tanwar
Harshita Makkar
Aditya Gupta (ORCID: https://orcid.org/0000-0002-3730-8944)
Seth Rachna
Sameer Bhakshi

Institutions

All India Institute of Medical Sciences (IN)

Publication Details

Journal: EJC Paediatric Oncology
Published: 2025-11-05
DOI: https://doi.org/10.1016/j.ejcped.2025.100408
Primary Topic: Acute Myeloid Leukemia Research
Type: article
Field-Weighted Citation Impact: 0.00

Controls

|||

ALL TIME

JAN

FEB

MAR

APR

MAY

JUN

JUL

AUG

SEP

OCT

article

THE GENOMIC LANDSCAPE OF JUVENILE MYELOMONOCYTIC LEUKEMIA ON WHOLE EXOME SEQUENCING

Meena Jagdish Prasad, Harsh Goel, Anita Chopra, Ravi Kumar Majhi et al.

Nov 5, 2025

EJC Paediatric Oncology

Acute Myeloid Leukemia Research

article

THE GENOMIC LANDSCAPE OF JUVENILE MYELOMONOCYTIC LEUKEMIA ON WHOLE EXOME SEQUENCING

Meena Jagdish Prasad, Harsh Goel, Anita Chopra, Ravi Kumar Majhi, Pranay Tanwar, Harshita Makkar, Aditya Gupta, Seth Rachna, Sameer Bhakshi

November 5, 2025article en

Abstract

Background: Juvenile Myelomonocytic Leukemia (JMML) is a rare myelodysplastic/myeloproliferative neoplasm. The RAS-pathway related genes are most commonly mutated in JMML. Other secondary mutations/alternative pathways are also thought to be involved in the pathogenesis. This study was prospectively done to map the mutational landscape of newly diagnosed and treatment naive JMML patients.

EJC Paediatric OncologyVol. 6

All India Institute of Medical Sciences (IN)

Openalex Percentile: Top 57%

Acute Myeloid Leukemia Research

DOI Open Access PDF OpenAlex

AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

THE GENOMIC LANDSCAPE OF JUVENILE MYELOMONOCYTIC LEUKEMIA ON WHOLE EXOME SEQUENCING — Meena Jagdish Prasad, Harsh Goel, et al. · EJC Paediatric Oncology (2025) | TGRS Research Map | TGRS