MYELODYSPLASTIC SYNDROME IN CHILDHOOD: THE HACETTEPE COHORT

NRAS alone 4.7% at diagnosis) with UBA1 mutation arising second (NRAS+UBA1: 27.3%).The NRAS+UBA1-mutant clone demonstrated myeloid bias compared to NRAS-only and wildtype cells.Purified CD34+ cells showed enrichment of both UBA1 and NRAS mutations, suggesting preferential expansion within hematopoietic stem/progenitor cells.Conclusions

Authors

Publication Details

Journal
EJC Paediatric Oncology
Published
2025-11-05
DOI
https://doi.org/10.1016/j.ejcped.2025.100407
Primary Topic
Myofascial pain diagnosis and treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

MYELODYSPLASTIC SYNDROME IN CHILDHOOD: THE HACETTEPE COHORT

Şule Ünal, Selin Aytaç, Barış Kuşkonmaz, Tekin Aksu et al.
EJC Paediatric Oncology
Myofascial pain diagnosis and treatment
article

MYELODYSPLASTIC SYNDROME IN CHILDHOOD: THE HACETTEPE COHORT

Şule Ünal, Selin Aytaç, Barış Kuşkonmaz, Tekin Aksu, Fatma Uğur
article en

Abstract

NRAS alone 4.7% at diagnosis) with UBA1 mutation arising second (NRAS+UBA1: 27.3%).The NRAS+UBA1-mutant clone demonstrated myeloid bias compared to NRAS-only and wildtype cells.Purified CD34+ cells showed enrichment of both UBA1 and NRAS mutations, suggesting preferential expansion within hematopoietic stem/progenitor cells.Conclusions

EJC Paediatric OncologyVol. 6
Openalex Percentile: Top 66%
Myofascial pain diagnosis and treatment
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