A study on the establishment of a traumatic brain injury model of tree shrews and the observation of neuroinflammatory responses
This study successfully constructed a TBI tree shrew model and confirmed that the polarization imbalance of microglia and astrocytes may form a neurotoxic microenvironment, ultimately causing brain tissue damage.
Authors
- Wen Yu (ORCID: https://orcid.org/0000-0002-9540-7924)
- J. Li (ORCID: https://orcid.org/0000-0002-7897-7618)
- Linbo Wang (ORCID: https://orcid.org/0000-0002-6982-103X)
- Xiaolina Zhang
- Linyi Chen (ORCID: https://orcid.org/0000-0001-7258-8817)
- Haiying Wu (ORCID: https://orcid.org/0009-0009-5083-2722)
- Jie Zhang (ORCID: https://orcid.org/0000-0003-2579-2537)
- Yang Li (ORCID: https://orcid.org/0000-0002-5850-3191)
- Jing Zhang (ORCID: https://orcid.org/0000-0001-8861-7336)
- Shengxiong Hong
- Yongjie Huang (ORCID: https://orcid.org/0000-0001-6692-9283)
Institutions
- Kunming Medical University (CN)
Publication Details
- Journal
- IBRO Neuroscience Reports
- Published
- 2025-11-05
- DOI
- https://doi.org/10.1016/j.ibneur.2025.11.003
- Primary Topic
- Neuroinflammation and Neurodegeneration Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00