Association of TNF-α polymorphisms rs1800629 (−308G>A) and rs361525 (−238G>A) with type 2 diabetes mellitus in the Punjabi population of Pakistan
In this Punjabi cohort from Pakistan, the A alleles of TNF-α promoter polymorphisms rs1800629 and rs361525 were significantly more frequent in T2DM cases, indicating that these variants increase susceptibility to T2DM in this population.
Authors
- Sawar Khan (ORCID: https://orcid.org/0000-0002-6928-7439)
- Umar Bin Abdul Aziz (ORCID: https://orcid.org/0009-0009-6266-4340)
- Chien‐Chin Chen (ORCID: https://orcid.org/0000-0001-9599-0884)
- Tsai-Sung Tai
- Muhammad Waqar (ORCID: https://orcid.org/0009-0001-4262-1337)
- Abdul Qadeer (ORCID: https://orcid.org/0000-0003-4804-1322)
- Mohammad Abohassan
Institutions
- Central South University (CN)
- University of Lahore (PK)
- National Chung Hsing University (TW)
- North West Agriculture and Forestry University (CN)
- Chia-Yi Christian Hospital (TW)
- Chia Nan University of Pharmacy and Science (TW)
- King Khalid University (SA)
- National Cheng Kung University (TW)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-11-05
- DOI
- https://doi.org/10.3389/fendo.2025.1664411
- Primary Topic
- Adipokines, Inflammation, and Metabolic Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- King Khalid University