Exposure to the herbicide glyphosate leads to inappropriate threat responses and alters gut microbial composition
Glyphosate increases threat interpretation and alters cellular activity in brain regions implicated in promoting anxiety. Also, glyphosate induces gut dysbiosis and reduces the abundance of <i>Lactobacillus</i>, bacteria that play a role in the production of serotonin, which may further exacerbate the anxiogenic effect of glyphosate.
Authors
- Filipa Godoy‐Vitorino (ORCID: https://orcid.org/0000-0003-1880-0498)
- Osmarie Martínez‐Guzmán
- Demetrio Sierra‐Mercado (ORCID: https://orcid.org/0000-0001-9080-9257)
- Alexdiel Figueroa‐Pérez
- Mauricio Cáceres‐Chacón
- Raúl Y. Ramos-Sánchez
- Hector A. Haddock‐Martínez
- Sian Rodriguez‐Rosado
- Jaleniz Suárez-Pérez
Institutions
- University of Puerto Rico, Medical Sciences Campus (PR)
- University of Puerto Rico System (PR)
Publication Details
- Journal
- Frontiers in Toxicology
- Published
- 2025-11-05
- DOI
- https://doi.org/10.3389/ftox.2025.1704231
- Citations
- 1
- Primary Topic
- Pesticide and Herbicide Environmental Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.50
Funders
- National Science Foundation
- National Institute of General Medical Sciences
- National Institute on Minority Health and Health Disparities