Integrative multi-omics analysis identifies TGFA as a novel glioma susceptibility gene and therapeutic target
TGFA is a novel glioma susceptibility gene with subtype-specific expression. Its therapeutic targeting offers opportunities for precision therapy, potentially advancing glioma clinical management.
Authors
- Gang Liu (ORCID: https://orcid.org/0000-0002-3163-3244)
- Nan Ji (ORCID: https://orcid.org/0000-0002-9001-8858)
- Shaohua Tu
- Zhigang Zhao (ORCID: https://orcid.org/0000-0003-0281-2259)
- Ruiqi Jiang (ORCID: https://orcid.org/0009-0006-5611-2214)
- Kefu Yu
Institutions
- Zhejiang International Studies University (CN)
- Capital Medical University (CN)
- Beijing Tian Tan Hospital (CN)
- Beijing Fengtai Hospital (CN)
Publication Details
- Journal
- Frontiers in Neurology
- Published
- 2025-11-05
- DOI
- https://doi.org/10.3389/fneur.2025.1656490
- Citations
- 1
- Primary Topic
- TGF-β signaling in diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.81