Differential impact of overt and subclinical hypothyroidism on severe postpartum hemorrhage: a retrospective cohort study
Overt hypothyroidism had a significant impact on the elevated risk of SPPH, especially in pregnant women aged < 35 years. In contrast, subclinical hypothyroidism showed no significant association with SPPH, which may reflect limited statistical power rather than the absence of risk. These findings offer valuable insights into the relationship between hypothyroidism and SPPH, potentially optimizing maternal outcomes by preventing and intervening in the occurrence of SPPH.
Authors
- Fang He (ORCID: https://orcid.org/0000-0003-3362-6002)
- Yujiao Fu (ORCID: https://orcid.org/0009-0007-6999-599X)
- Li Tang (ORCID: https://orcid.org/0000-0001-5468-985X)
- Qi Guo (ORCID: https://orcid.org/0000-0002-0193-4388)
- Chenning Liu (ORCID: https://orcid.org/0000-0003-4298-7416)
- Jinmu Zhuang
- Yu-Hui Liu (ORCID: https://orcid.org/0009-0004-7700-3522)
Institutions
- University of Macau (MO)
- Third Affiliated Hospital of Guangzhou Medical University (CN)
- Dongguan People’s Hospital (CN)
- Guangdong Provincial Center for Disease Control and Prevention (CN)
- Southern Medical University (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-11-05
- DOI
- https://doi.org/10.3389/fendo.2025.1654856
- Citations
- 1
- Primary Topic
- Thyroid Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.29
Funders
- National Key Research and Development Program of China