Tislelizumab-associated toxic epidermal necrolysis in an esophageal cancer patient: a case report
This case illustrates that tislelizumab can induce TEN after a prolonged incubation period (86 days in this instance). It underscores the importance of vigilant monitoring of skin and mucous membranes during treatment, early recognition and intervention, and adequate glucocorticoid dosing in managing this serious immune-related adverse event, offering valuable clinical insight for oncologists.
Authors
- Zehu Liu
- Sha Jin (ORCID: https://orcid.org/0000-0001-8256-0682)
- Zheng Fu (ORCID: https://orcid.org/0000-0002-7483-832X)
Institutions
- Third People's Hospital of Hangzhou (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-11-05
- DOI
- https://doi.org/10.3389/fimmu.2025.1707956
- Citations
- 1
- Primary Topic
- Drug-Induced Adverse Reactions
- Type
- article
- Field-Weighted Citation Impact
- 1.39