Tislelizumab-associated toxic epidermal necrolysis in an esophageal cancer patient: a case report

This case illustrates that tislelizumab can induce TEN after a prolonged incubation period (86 days in this instance). It underscores the importance of vigilant monitoring of skin and mucous membranes during treatment, early recognition and intervention, and adequate glucocorticoid dosing in managing this serious immune-related adverse event, offering valuable clinical insight for oncologists.

Authors

Institutions

Publication Details

Journal
Frontiers in Immunology
Published
2025-11-05
DOI
https://doi.org/10.3389/fimmu.2025.1707956
Citations
1
Primary Topic
Drug-Induced Adverse Reactions
Type
article
Field-Weighted Citation Impact
1.39
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Tislelizumab-associated toxic epidermal necrolysis in an esophageal cancer patient: a case report

Zehu Liu, Sha Jin, Zheng Fu
1 citations
Frontiers in Immunology
Drug-Induced Adverse Reactions
1.39
article

Tislelizumab-associated toxic epidermal necrolysis in an esophageal cancer patient: a case report

Zehu Liu, Sha Jin, Zheng Fu
article en
1 citations

Abstract

This case illustrates that tislelizumab can induce TEN after a prolonged incubation period (86 days in this instance). It underscores the importance of vigilant monitoring of skin and mucous membranes during treatment, early recognition and intervention, and adequate glucocorticoid dosing in managing this serious immune-related adverse event, offering valuable clinical insight for oncologists.

Frontiers in ImmunologyVol. 16
Third People's Hospital of Hangzhou (CN)
Openalex Percentile: Top 15%
Drug-Induced Adverse Reactions
1.39
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.