Acanthamoeba spp. genotypes demonstrate genotype-specific motility and encystment differences in both fed and starved environments

Overall, these results indicate that eight of the common genotypes of <i>Acanthamoeba</i> vary widely in terms of size, speed, rates of encystment, and response to nutritional state. From these, we can infer that <i>Acanthamoeba</i> keratitis prevention methods must be robust enough to counter amoeba in trophozoite or cyst form, and that amoeba should be expected to be able to traverse a wide variety of distances (for instance, across a contact lens or onto a corneal epithelium) in either a fed or starved nutritional state.

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Publication Details

Journal
Frontiers in Ophthalmology
Published
2025-11-05
DOI
https://doi.org/10.3389/fopht.2025.1684686
Primary Topic
Legionella and Acanthamoeba research
Type
article
Field-Weighted Citation Impact
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article

Acanthamoeba spp. genotypes demonstrate genotype-specific motility and encystment differences in both fed and starved environments

Allison Campolo, Monica Crary, Esther Lara
Frontiers in Ophthalmology
Legionella and Acanthamoeba research
article

Acanthamoeba spp. genotypes demonstrate genotype-specific motility and encystment differences in both fed and starved environments

Allison Campolo, Monica Crary, Esther Lara
article en

Abstract

Overall, these results indicate that eight of the common genotypes of <i>Acanthamoeba</i> vary widely in terms of size, speed, rates of encystment, and response to nutritional state. From these, we can infer that <i>Acanthamoeba</i> keratitis prevention methods must be robust enough to counter amoeba in trophozoite or cyst form, and that amoeba should be expected to be able to traverse a wide variety of distances (for instance, across a contact lens or onto a corneal epithelium) in either a fed or starved nutritional state.

Frontiers in OphthalmologyVol. 5
Alcon (United States) (US)
Openalex Percentile: Top 72%
Legionella and Acanthamoeba research
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