Use of thyroid hormones in euthyroid patients with unexplained fatigue: analyses of aggregate data from European national surveys of professional endocrine society members
A small, yet not negligible percentage of European thyroid-focused physicians consider using TH for euthyroid patients with unexplained fatigue, with significant variations based on geographic, demographic, and practice-related factors. Using levothyroxine and/or liothyronine in such cases lacks evidence and may partially contribute to the concerning overuse of TH therapy.
Authors
- Roberto Attanasio (ORCID: https://orcid.org/0000-0002-1417-287X)
- Ersin Akarsu (ORCID: https://orcid.org/0000-0003-2786-6616)
- D Niculescu (ORCID: https://orcid.org/0000-0002-6439-3523)
- Maria Alevizaki (ORCID: https://orcid.org/0000-0003-3726-5793)
- Chagit Adler Cohen
- Cătălina Poiană (ORCID: https://orcid.org/0000-0002-5795-3318)
- Juan C. Galofré (ORCID: https://orcid.org/0000-0003-0227-3566)
- Harald Dobnig (ORCID: https://orcid.org/0000-0001-7574-9292)
- Roberto Negro (ORCID: https://orcid.org/0000-0002-4319-5923)
- Laurence Leenhardt (ORCID: https://orcid.org/0000-0003-4131-6813)
- Maria‐Cristina Burlacu (ORCID: https://orcid.org/0000-0002-8437-3933)
- Petros Perros (ORCID: https://orcid.org/0000-0001-7320-5574)
- М.D. Тronko (ORCID: https://orcid.org/0000-0001-7421-0981)
- Marek Ruchała (ORCID: https://orcid.org/0000-0002-6296-7220)
- Eszter Berta (ORCID: https://orcid.org/0000-0003-0439-9867)
- Т. Б. Моргунова (ORCID: https://orcid.org/0000-0003-1500-1586)
- Alla Shepelkevich (ORCID: https://orcid.org/0000-0002-8213-2968)
- Anna-Maria Borissova (ORCID: https://orcid.org/0000-0003-0553-408X)
- Stephen Ludgate (ORCID: https://orcid.org/0000-0002-9597-9471)
- Enrico Papini (ORCID: https://orcid.org/0000-0003-4790-2733)
- Andromachi Vryonidou (ORCID: https://orcid.org/0000-0002-0544-5952)
- Miguel Melo (ORCID: https://orcid.org/0000-0003-4050-3473)
- Martin Kužma (ORCID: https://orcid.org/0000-0002-1294-1217)
- W. Edward Visser (ORCID: https://orcid.org/0000-0002-5248-863X)
- Michal Kršek (ORCID: https://orcid.org/0000-0002-5941-3489)
- László Hegedüs (ORCID: https://orcid.org/0000-0002-9691-7619)
- Saara Metso (ORCID: https://orcid.org/0000-0001-8197-7603)
- David Unuane (ORCID: https://orcid.org/0000-0002-8488-1735)
- Anne McGowan (ORCID: https://orcid.org/0000-0003-4222-622X)
- Francisca Marques Puga (ORCID: https://orcid.org/0000-0002-9510-419X)
- Jacob Stampe Frølich (ORCID: https://orcid.org/0000-0001-8156-2424)
- Tereza Planck (ORCID: https://orcid.org/0000-0003-1398-5067)
- Mihail Boyanov (ORCID: https://orcid.org/0000-0002-5695-2831)
- Eyal Robenshtok (ORCID: https://orcid.org/0000-0002-6268-4212)
- Younes R. Younes (ORCID: https://orcid.org/0000-0003-0929-1003)
- Elena Yurenya (ORCID: https://orcid.org/0000-0002-6836-3794)
- Camille Buffet (ORCID: https://orcid.org/0000-0003-1389-4157)
- Michael Krebs (ORCID: https://orcid.org/0000-0002-9265-7274)
- Peter Kopp (ORCID: https://orcid.org/0000-0001-5980-0529)
- Jan Jiskra (ORCID: https://orcid.org/0000-0003-0920-4854)
- Irfan Vardarli (ORCID: https://orcid.org/0009-0009-2554-0971)
- Kamilla Ryom Riis (ORCID: https://orcid.org/0000-0003-2679-7153)
- Biljana Nedeljković-Beleslin (ORCID: https://orcid.org/0000-0002-1687-9297)
- Tomasz Bednarczuk (ORCID: https://orcid.org/0000-0002-5752-8709)
- Eric Fliers (ORCID: https://orcid.org/0000-0001-8048-9050)
- Ivica Lazúrová (ORCID: https://orcid.org/0000-0002-3163-1097)
- Miklós Bodor (ORCID: https://orcid.org/0000-0002-0789-5156)
- Miloš Žarković (ORCID: https://orcid.org/0000-0001-9977-5970)
- Juan J. Díez (ORCID: https://orcid.org/0000-0002-2017-0694)
- Benjamin C. T. Field (ORCID: https://orcid.org/0000-0002-1883-1588)
- Tommi Hakala (ORCID: https://orcid.org/0000-0002-9373-4462)
- Endre Vezekenyi Nagy (ORCID: https://orcid.org/0000-0002-9286-6471)
- Göksün Ayvaz (ORCID: https://orcid.org/0000-0002-1213-6832)
- Carla Moran (ORCID: https://orcid.org/0000-0002-7318-7166)
- Božidar Perić (ORCID: https://orcid.org/0000-0001-9998-4895)
- Patrick Olivier Rosselet (ORCID: https://orcid.org/0009-0004-3793-8163)
- J. Ćirić
- Dagmar Führer‐Sakel
- Valentin Fadeyev
- Vitaliy Luchytskiy
- Aleksandra Sugier
Institutions
- University College Dublin (IE)
- Poznan University of Medical Sciences (PL)
- Cliniques Universitaires Saint-Luc (BE)
- University of Debrecen (HU)
- Vrije Universiteit Brussel (BE)
- Carol Davila University of Medicine and Pharmacy (RO)
- Tel Aviv University (IL)
- Sechenov University (RU)
- National and Kapodistrian University of Athens (GR)
- University of Pavol Jozef Šafárik (SK)
- Trinity College Dublin (IE)
- Charles University (CZ)
- Heidelberg University (DE)
- Medical University of Warsaw (PL)
- Alexandrovska Hospital (BG)
- Rabin Medical Center (IL)
- Odense University Hospital (DK)
- East Surrey Hospital (GB)
- Beaumont Hospital (IE)
- Erasmus MC (NL)
- University Hospital Heidelberg (DE)
- Tallaght University Hospital (IE)
- University of Surrey (GB)
- Medical University of Sofia (BG)
- Hospital de São João (PT)
- Sorbonne Université (FR)
- University of Belgrade (RS)
- Noguchi Thyroid Clinic and Hospital Foundation (JP)
- Assistance Publique – Hôpitaux de Paris (FR)
- Hellenic Red Cross (GR)
- Memorial Ankara Hospital (TR)
- Red Cross Hospital (GR)
- Hospital Universitario Puerta de Hierro Majadahonda (ES)
- Navarre Institute of Health Research (ES)
- Alexandra Hospital (GR)
- St. Vincent's University Hospital (IE)
- Knappschaftskrankenhaus Recklinghausen (DE)
- Essen University Hospital (DE)
- Pitié-Salpêtrière Hospital (FR)
- Sisters of Charity Hospital (HR)
- Tampere University Hospital (FI)
- V.P. Komisarenko Institute of Endocrinology and Metabolism (UA)
- Tampere University (FI)
- Clinica Universidad de Navarra (ES)
- Skåne University Hospital (SE)
- Ospedale Regina Apostolorum (IT)
- Associazione Medici Diabetologi (IT)
- Instituto de Investigación Sanitaria de Santiago (ES)
- Amsterdam University Medical Centers (NL)
- Ospedale Vito Fazzi (IT)
- University Medical Centre Mannheim (DE)
- Surrey and Sussex Healthcare NHS Trust (GB)
- Groupe de recherche clinique – Tumeurs Thyroïdiennes
- Belarusian State Medical University (BY)
- Sofia University "St. Kliment Ohridski" (BG)
- Gaziantep University (TR)
- Universidad Autónoma de Madrid (ES)
- Comenius University Bratislava (SK)
- Medical University of Vienna (AT)
- University of Coimbra (PT)
- Newcastle University (GB)
- University of Amsterdam (NL)
- Erasmus University Rotterdam (NL)
- UCLouvain (BE)
- University of Lausanne (CH)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-11-05
- DOI
- https://doi.org/10.3389/fendo.2025.1713814
- Primary Topic
- Thyroid Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00