Prostate cancer evolution after COVID-19-related prostatitis in a TMPRSS2-altered patient: a case report and review of the molecular interface between SARS-CoV-2 and prostate oncogenesis
This is the first documented case suggesting a potential link between COVID-19-related prostatitis and subsequent prostate cancer in a TMPRSS2::ERG-altered patient without hereditary predisposition. Although causality cannot be established, the findings highlight a hypothesis-generating interface between viral infection, inflammation, and oncogenesis that warrants further study.
Authors
- Fabrício Borges Carrerette (ORCID: https://orcid.org/0000-0002-7678-7589)
- Daniela Bouzas Rodeiro
- Felipe Leite Guedes (ORCID: https://orcid.org/0000-0002-8348-0323)
- António Polónia (ORCID: https://orcid.org/0000-0001-8312-1681)
- Fábio dos Santos Santiago
- João S. T. Coelho
- Ana Oliveira (ORCID: https://orcid.org/0000-0002-4977-5136)
- Romulo Varella de Oliveira (ORCID: https://orcid.org/0000-0002-0073-5811)
- Magda Conceição Barbosa Gomes
Institutions
- Hospital Universitário Pedro Ernesto (BR)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-11-05
- DOI
- https://doi.org/10.3389/fonc.2025.1679663
- Primary Topic
- COVID-19 Impact on Reproduction
- Type
- article
- Field-Weighted Citation Impact
- 0.00