Melanoma of the Choroid and Ciliary Body in Children: Remission of Metastatic Melanoma of the Choroid After Treatment With Chemotherapy and Immune Checkpoint Inhibition
This report underscores the rarity and diverse presentation of pediatric choroidal melanoma. Diagnosis of LFS in one patient highlights the importance of genetic testing for tumor predisposition and personalized approaches in managing rare pediatric tumors.
Authors
- Petra Ketteler (ORCID: https://orcid.org/0000-0002-8138-0441)
- Karen Fischhuber (ORCID: https://orcid.org/0000-0002-5417-6875)
- Saskia Ting (ORCID: https://orcid.org/0000-0003-1415-7714)
- Ines B. Brecht (ORCID: https://orcid.org/0000-0001-7973-3300)
- Eva Biewald (ORCID: https://orcid.org/0000-0002-5941-1686)
- Pia Tüller (ORCID: https://orcid.org/0009-0003-1498-8064)
- Tobias Kiefer
- Cordula Kiewert
- Elisabeth Livingstone (ORCID: https://orcid.org/0000-0001-8279-9239)
- Leyla Jabbarli (ORCID: https://orcid.org/0000-0001-7370-5077)
- Sophia Göricke
- Lisa Zimmer (ORCID: https://orcid.org/0000-0002-3680-3521)
- Kyriaki Papaioannou
- Andreas Junker (ORCID: https://orcid.org/0000-0002-8063-9765)
- Nikolaos Emmanouel Bechrakis (ORCID: https://orcid.org/0000-0002-0180-1112)
- Nicole Barwinski
- Stefan Schönberger (ORCID: https://orcid.org/0000-0002-7222-296X)
- Dominik T. Schneider (ORCID: https://orcid.org/0000-0001-8153-1601)
- Kathrin Schramm (ORCID: https://orcid.org/0009-0006-7355-6378)
Institutions
- University of Kassel (DE)
- German Cancer Research Center (DE)
- Heidelberg University (DE)
- National Center for Tumor Diseases (DE)
- Hopp Children's Cancer Center Heidelberg (DE)
- Essen University Hospital (DE)
- University Children's Hospital Tübingen (DE)
- Klinikum Dortmund (DE)
- Deutsches Konsortium für Translationale Krebsforschung (DE)
- University of Duisburg-Essen (DE)
Publication Details
- Journal
- Pediatric Blood & Cancer
- Published
- 2025-11-04
- DOI
- https://doi.org/10.1002/pbc.32147
- Citations
- 1
- Primary Topic
- Ocular Oncology and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.71
Funders
- Deutsches Krebsforschungszentrum
- Bundesministerium für Bildung und Forschung
- Bundesministerium für Gesundheit
- Deutsche Krebshilfe
- Deutsche Kinderkrebsstiftung
- Deutschen Konsortium für Translationale Krebsforschung