Comparison of topical hypericum perforatum and metformin effectiveness in wound healing in streptozotocin-induced diabetic rats
Topically applied HP in uncontrolled DM rats improved wound healing scores more than the non-diabetic controls. Metformin also significantly enhanced healing in DM rats, with results comparable to controls. Since HP and metformin are easily accessible, further research could lead to cost-effective treatments for wound healing issues in DM patients.
Authors
- Mehmet Arıcan (ORCID: https://orcid.org/0000-0002-0649-2339)
- Mehmet Alı Sungur (ORCID: https://orcid.org/0000-0001-5380-0819)
- Zekeriya Okan Karaduman (ORCID: https://orcid.org/0000-0002-6719-3666)
- Sönmez Sağlam (ORCID: https://orcid.org/0000-0003-2651-8003)
- Fatih Demir (ORCID: https://orcid.org/0000-0002-8181-0739)
- Raşit Emin Dalaslan (ORCID: https://orcid.org/0000-0001-5068-8024)
- Murat Yücel (ORCID: https://orcid.org/0000-0003-0220-9230)
- Banu Turhan
Institutions
- Ankara Atatürk Eğitim ve Araştırma Hastanesi (TR)
- Education Training And Research (US)
- Düzce Üniversitesi (TR)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-11-05
- DOI
- https://doi.org/10.3389/fendo.2025.1691294
- Citations
- 1
- Primary Topic
- Wound Healing and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.03