Identification of glycolysis-related clusters and immune cell infiltration in hepatic fibrosis progression using machine learning models and experimental validation
Glycolytic reprogramming is a key pathogenic driver in HF progression and associated immune infiltration. Investigating this metabolic-immune dysregulation represents a promising therapeutic focus for progression of HF.
Authors
- Hong Ren (ORCID: https://orcid.org/0000-0002-4557-0918)
- Ke Qiu (ORCID: https://orcid.org/0000-0001-9493-0345)
- Zhihui Deng (ORCID: https://orcid.org/0000-0002-2046-1467)
- A L Li
- Guanglin Xiao (ORCID: https://orcid.org/0000-0002-4270-3914)
- Xia Yi (ORCID: https://orcid.org/0000-0003-4427-5738)
Institutions
- Dalian Medical University (CN)
- Second Affiliated Hospital of Chongqing Medical University (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-11-05
- DOI
- https://doi.org/10.3389/fimmu.2025.1684937
- Primary Topic
- Liver physiology and pathology
- Type
- article
- Field-Weighted Citation Impact
- 0.00