Giant Cell Tumor with Chondroid Differentiation: A Case Report on This Rare Morphological Variant and a Diagnostic Challenge
This report details the radiological and pathological findings of the GCT of distal femur exhibiting cartilage matrix. It behaves as a GCT without cartilage matrix and should be treated accordingly. Furthermore, immunohistochemical staining with antibodies against the mutant-specific H3.3 protein or identification of H3.3G34A guides us for confirmation of diagnosis.
Authors
- Nikhil Tandon (ORCID: https://orcid.org/0000-0003-4604-1986)
- Deepander Singh Rathore
- Sankalp Sancheti (ORCID: https://orcid.org/0000-0001-5810-8733)
- Pradeep Kumar (ORCID: https://orcid.org/0000-0001-6407-703X)
- Ashish Gulia
Institutions
- Bhabha Hospital (IN)
- Cancer Hospital and Research Institute (IN)
Publication Details
- Journal
- Journal of Orthopaedic Case Reports
- Published
- 2025-01-01
- DOI
- https://doi.org/10.13107/jocr.2025.v15.i11.6342
- Primary Topic
- Bone Tumor Diagnosis and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00