A Novel Immunohistochemistry Classifier for Ampullary Carcinoma: Highlighting the Prognostic Power of <scp>CDX2</scp>

The PB subtype showed a higher pathological tumor stage than INT. Among the various schemas evaluated, the Harthimmer Integrated Liu Layered Scoring system performed best with a significant correlation between HE and IHC subtypes. INT subtypes had better prognostic outcomes than PB subtypes. We found an essential prognostic role of CDX2 in the stratification of ACs.

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Publication Details

Journal
Journal of Hepato-Biliary-Pancreatic Sciences
Published
2025-11-04
DOI
https://doi.org/10.1002/jhbp.70021
Primary Topic
Pancreatic and Hepatic Oncology Research
Type
article
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article

A Novel Immunohistochemistry Classifier for Ampullary Carcinoma: Highlighting the Prognostic Power of CDX2

Thomas Alex Kodiatte, Rijo Issac, Shailaja Balakumar, M. J. Aparna et al.
Journal of Hepato-Biliary-Pancreatic Sciences
Pancreatic and Hepatic Oncology Research
article

A Novel Immunohistochemistry Classifier for Ampullary Carcinoma: Highlighting the Prognostic Power of CDX2

Thomas Alex Kodiatte, Rijo Issac, Shailaja Balakumar, M. J. Aparna, Raiza Philip
article en

Abstract

The PB subtype showed a higher pathological tumor stage than INT. Among the various schemas evaluated, the Harthimmer Integrated Liu Layered Scoring system performed best with a significant correlation between HE and IHC subtypes. INT subtypes had better prognostic outcomes than PB subtypes. We found an essential prognostic role of CDX2 in the stratification of ACs.

Journal of Hepato-Biliary-Pancreatic SciencesVol. 32(12)
Christian Medical College, Vellore (IN), Christian Medical College (IN)
Openalex Percentile: Top 56%
Pancreatic and Hepatic Oncology Research
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