TMEtyper: A computational method for tumor microenvironment subtyping with applications in immunotherapy
TMEtyper establishes an integrative framework that advances TME characterization beyond conventional classifications, delivering both biological insights and clinical utility. Its deployment as an accessible analytical resource opens new avenues for personalized immunotherapy strategies and biomarker development.
Authors
- Ya‐Ru Miao
- Yanghui Bi (ORCID: https://orcid.org/0000-0002-4452-6800)
- Yan Li (ORCID: https://orcid.org/0000-0001-9360-2075)
- Ruiping Zhang (ORCID: https://orcid.org/0000-0001-6922-0747)
- Jie Yao (ORCID: https://orcid.org/0000-0003-2539-0167)
- Tong Zhou (ORCID: https://orcid.org/0000-0002-3917-4476)
Institutions
- Shanxi Medical University (CN)
- Jiangsu Provincial Center for Disease Control and Prevention (CN)
- Shanxi Academy of Medical Sciences (CN)
Publication Details
- Journal
- Computational and Structural Biotechnology Journal
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1016/j.csbj.2025.10.053
- Primary Topic
- Single-cell and spatial transcriptomics
- Type
- article
- Field-Weighted Citation Impact
- 0.00