Barriers to Investigator-Initiated Clinical Trial Enrollment in Frontline Large B-Cell Lymphoma
Geographic distance and neighborhood deprivation significantly influenced trial enrollment, even in investigator-initiated trials (IITs). Decentralized trial models, telemedicine triage, and system-level interventions are needed to reduce these inequities.
Authors
- Vikram Raghunathan (ORCID: https://orcid.org/0000-0002-6026-4134)
- Ajay K. Gopal (ORCID: https://orcid.org/0000-0003-3023-6834)
- Ryan C. Lynch (ORCID: https://orcid.org/0000-0001-6703-0894)
- Qian Wu (ORCID: https://orcid.org/0000-0002-2292-4816)
- Brian G. Till (ORCID: https://orcid.org/0000-0002-4718-8288)
- Heather Rasmussen (ORCID: https://orcid.org/0000-0002-0622-1985)
- Christina Poh (ORCID: https://orcid.org/0000-0003-3120-712X)
- Kevin Ng
- Mengyang Di (ORCID: https://orcid.org/0000-0001-6165-2617)
- Neena Kennedy
- Chaitra S. Ujjani (ORCID: https://orcid.org/0000-0003-1977-1510)
- Carrie Ho (ORCID: https://orcid.org/0000-0003-4437-9377)
- Stephen D. Smith (ORCID: https://orcid.org/0000-0001-5354-7593)
- Mazyar Shadman
Institutions
- University of California, San Francisco (US)
- Fred Hutch Cancer Center (US)
Publication Details
- Journal
- Clinical Lymphoma Myeloma & Leukemia
- Published
- 2025-11-05
- DOI
- https://doi.org/10.1016/j.clml.2025.11.002
- Primary Topic
- Acute Lymphoblastic Leukemia research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Heart, Lung, and Blood Institute